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pentobarbital will lower the level or impact of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will decrease the level or impact of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Advised atogepant dosage with concomitant utilization o